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The Italian Serie A League is back, and at Topbets, we will be giving you a prediction for every match day.
While punters prefer to back former giants in the slips, Topbets will be keen on analysis games based on form, squad and previous head-to-head encounters each week.
Serie A Round 5 Predictions
Saturday 27th September
Como v Cremonese
Both teams have started the season in a way that would please both fan bases, as Como has 7 points to Cremonese’s 8. This will be another close tie, but Cremonese should be confident having beaten Como in 5 of their last 6 H2H meetings
- Tip 1: Cremonese Win
- Tip 2: BTTS
- Tip 3: Over 2.5 Goals
Where to bet: Melbet, 22bet, Betjara
Juventus v Atalanta
The second-placed team comes against the 5th placed team in Serie A in one of the most anticipated clashes in Italy this weekend. While Juve have dominated this tie, winning 30 of their 48 encounters, they come against an Atalanta side who are fighting to close the gap between them and the top teams.
- Tip 1: Nikola Krstovic to Score
- Tip 2: Under 2.5 Goals.
- Tip 3: Draw
Where to bet: Melbet, 22bet, Betjara
Cagliari v Inter
Cagliari sits on top of Inter Milan coming into this game, but they have struggled against Inter in recent H2H games, and with Inter looking to bounce back from their slow start to this season, this is a tie they will fancy.
- Tip 1: Inter Win
- Tip: Marcus Thuram to Score
- Tip 3: Over 2.5 Goals
Where to bet: Melbet, 22bet, Betjara

Sunday 28th September 2025
Sassuolo v Udinese
The last three meetings between the two sides have ended in draws, and with Sassuolo currently struggling in the game, they might feel this is a game that should spark their recharge, but they are against a Udinese side who are 9th on the table.
- Tip 1: Draw
- Tip 2: BTTS
- Tip 3: Udinese Win
Roma v Verona
Both teams have had contrasting starts to the season, where the hosts have been flying while Verona has been hapless. Roma has always dominated this fixture, winning 5 of their last 6 H2H meetings.
- Tip 1: Roma Win
- Tip 2: Over 2.5 Goals
- Tip 3: BTTS
Pisa v Fiorentina
Pisa proved that they can score goals in their last, where they managed 2 against Napoli. They are up against a Fiorentina side who are struggling too, so they would want to lock their defence and hope that they can conjure a win.
- Tip 1: Under 2.5 Goals.
- Tip 2: Draw:
- Tip 3: Over 5 Corners.
Lecce v Bologna
Lecce has suffered 2 losses in their last 3 home games, while Bologna has suffered losses in their last 3 Serie A away games. While Lecce have struggled against Bologna in their H2H meetings, they would want to give their all at the Stadio Comunale Via del Mare.
- Tip 1: Bologna Win
- Tip 2: Under 2.5 Goals
- Tip 3: Winner to keep a clean sheet
Milan v Napoli
This is Serie A’s game of the week. Encounters between the two sides have been close calls. Only four points separate the two, and with Milan trying hard to bring back their glory days, they should feel confident in their bid to close the gap between them and the league leaders.
- Tip 1: Over 2.5 Goals
- Tip 2: BTTS
- Tip 3: Christian Pulisic or Hojlund to Score
Monday 29th September 2025
Parma v Torino
Parma has seen 3 draws in their last 6 games against Torino, but both teams are keen on winning to move up the table. Parma are currently 18th with Torino being 12th but both teams are just separated by two points.
- Tip 1: Under 2.5 Goals
- Tip 2: Over 6 yellow cards
- Tip 3: Draw
Genoa v Lazio
Genoa has always struggled against Lazio, but both teams are yet to hit the required height this season. Lazio has been beaten in 4 of their last 6 Serie A games with Genoa losing 1 of their last 2 home games.
Tip 3: Lazio Win
Tip 1: Under 2.5 Goals
Tip 2: Winner to keep a clean sheet.
Serie A Table & Fixtures
Serie A results
Serie A Round Four Results
Lecce v Cagliari
- Tip 1: Draw❌
- Tip 2: Cagliari Win✅
- Tip 3: BTTS✅
Bologna v Genoa
- Tip 1: Draw❌
- Tip 2: BTTS✅
- Tip 3: Under 2.5 Goals❌
Verona v Juventus
- Tip 1: Juventus Win❌
- Tip 2: Juve to keep a clean sheet❌
- Tip 3: Over 2.5 Goals❌
Udinese v AC Milan
- Tip 1: Milan Win✅
- Tip 2: Under 2.5 Goals❌
- Tip 3: Christian Pulisic to Score✅
Lazio v AS Roma
- Tip 1: Under 2.5 Goals✅
- Tip 2: Red Card in the game✅
- Tip 3: Roma Win✅
Torino v Atalanta
- Tip 1: Over 2.5 Goals✅
- Tip 2: BTTS❌
- Tip 3: Atalanta Win✅
Cremonese v Parma
- Tip 1: Cremonese Win❌
- Tip 2: Over 2.5 Goals❌
- Tip 3: BTTS❌
Fiorentina v Como
- Tip 1: BTTS✅
- Tip 2: Fiorentina Win❌
- Tip 3: Over 2.5 Goals✅
Inter Milan v Sassuolo
- Tip 1: Inter Win✅
- Tip 2: Marcus Thuram to score❌
- Tip 3: Over 2.5 Goals✅
Napoli v Pisa
Tip 3: Over 2.5 Goals✅
Tip 1: Napoli Win ✅
Tip 2: Hojlund to Score❌
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